Johanna Chiche Selected Research

Radiotherapy

1/2015	Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.
1/2012	Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis.

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Johanna Chiche Research Topics

Disease

24	Neoplasms (Cancer) 01/2022 - 04/2007
11	Hypoxia (Hypoxemia) 10/2021 - 04/2007
5	B-Cell Lymphoma (Lymphoma, B Cell) 01/2022 - 01/2018
4	Acidosis 01/2012 - 04/2007
3	Lymphoma (Lymphomas) 01/2019 - 10/2013
2	Carcinogenesis 10/2013 - 10/2011
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023
1	Leukemia 01/2022
1	Lung Neoplasms (Lung Cancer) 10/2021
1	Erythema 01/2019
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2019
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2018
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2018
1	Adenocarcinoma of Lung 09/2017
1	Neoplasm Metastasis (Metastasis) 01/2015
1	T-Cell Lymphoma (Lymphoma, T Cell) 06/2013
1	Necrosis 04/2012
1	Carcinoma (Carcinomatosis) 01/2012
1	Colonic Neoplasms (Colon Cancer) 10/2011

Drug/Important Bio-Agent (IBA)

5	Oxygen (Dioxygen)IBA 01/2015 - 04/2007
5	Carbonic Anhydrases (Carbonic Anhydrase)IBA 06/2013 - 01/2010
5	Transcription Factors (Transcription Factor)IBA 05/2013 - 04/2007
4	Carbonic Anhydrase IXIBA 10/2017 - 01/2009
4	AcidsIBA 09/2013 - 04/2010
4	EnzymesIBA 05/2013 - 01/2009
3	Proteins (Proteins, Gene)FDA Link 10/2021 - 10/2011
3	CarbohydratesIBA 01/2018 - 10/2011
3	Adenosine Triphosphate (ATP)IBA 09/2013 - 01/2009
3	Lactic Acid (Lactate)FDA LinkGeneric 04/2012 - 04/2007
2	Asparaginase (Elspar)FDA Link 01/2022 - 01/2019
2	Messenger RNA (mRNA)IBA 01/2022 - 01/2009
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2019 - 01/2018
2	CytokinesIBA 01/2019 - 01/2018
2	Deoxyglucose (2 Deoxy D glucose)IBA 10/2013 - 12/2012
2	Protons (Proton)IBA 09/2013 - 04/2012
2	Protein Isoforms (Isoforms)IBA 06/2013 - 01/2009
2	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 05/2013 - 10/2011
2	Small Interfering RNA (siRNA)IBA 10/2011 - 05/2009
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2023
1	Aspartate-Ammonia Ligase (Asparagine Synthetase)IBA 01/2022
1	AsparagineIBA 01/2022
1	GlutaminaseIBA 01/2022
1	Glutamine (L-Glutamine)FDA Link 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Ribonucleases (Ribonuclease)IBA 01/2022
1	Amino Acids FDA Link 11/2021
1	IsotopesIBA 11/2021
1	Metformin (Glucophage)FDA LinkGeneric 10/2021
1	Indicators and Reagents (Reagents)IBA 10/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021
1	Apoptosis Regulatory ProteinsIBA 01/2021
1	N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketoneIBA 01/2019
1	Phenformin (Fenformin)IBA 01/2019
1	CaspasesIBA 01/2019
1	Caspase 1 (ICE Protease)IBA 01/2019
1	alanylaspartic acidIBA 01/2019
1	MTOR InhibitorsIBA 01/2018
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 10/2017
1	ZincIBA 10/2017
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 09/2017
1	carbonic anhydrase XIIIBA 06/2013
1	Cytotoxins (Cytolysins)IBA 12/2012
1	Neoplasm Antigens (Tumor Antigens)IBA 12/2012
1	IsoenzymesIBA 10/2011
1	SymportersIBA 10/2011
1	AR C155858IBA 10/2011
1	Etoposide (VP 16)FDA LinkGeneric 03/2010
1	StaurosporineIBA 03/2010
1	Bicarbonates (Hydrogen Carbonate)IBA 01/2009
1	Glucose (Dextrose)FDA LinkGeneric 04/2007

Therapy/Procedure

11	Therapeutics 10/2021 - 02/2011
6	Drug Therapy (Chemotherapy) 01/2023 - 03/2010
2	Radiotherapy 01/2015 - 01/2012
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2019
1	Diet Therapy (Therapy, Diet) 01/2018
1	Caloric Restriction 10/2013